|Generic Medication||Brand Names||Dosage Forms||Starting Dose||Max Dose||Notes|
|Guanfacine (extended release)||Intuniv||1 mg, 2 mg, 3 mg, 4 mg||1 mg daily||4 mg in children 6-12; 7 mg in children 13+||α-agonist (α2A-specific) Orthostasis, sedation Can be given morning or evening; can be used together with stimulant|
|Clonidine (extended release tablet)||Kapvay||0.1 mg||0.1 mg daily to BID||0.2mg BID||α-agonist (less specific for α2A) BID dosing if higher than 0.1 mg per day|
|Atomoxetine||Strattera||10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg, 100 mg||10 mg daily||100mg daily||Capsule cannot be opened|
|Viloxazine (extended release)||Qelbree||100 mg, 150 mg, 200 mg||25 mg daily||70 mg daily (85 mg daily for adults)||Capsule can be opened and sprinkled|
Guanfacine and clonidine are alpha agonists; atomoxetine and viloxazine are norepinephrine reuptake inhibitors.
See the Ohio Department of Medicaid Unified Preferred Drugs List for information about prescription coverage for children enrolled in Medicaid.
Common Side Effects for Alpha Agonists (guanfacine and clonidine)
Lightheadedness/dizziness, especially when sitting up or standing up; mild sedation; headache.
Serious Side Effects for Alpha Agonists (Rare)
Syncope (fainting); large decreases in heart rate or blood pressure.
Common Side Effects for norepinephrine reuptake inhibitors (atomoxetine and viloxazine)
Gastrointestinal side effects: upset stomach, diarrhea, nausea, vomiting, reduced appetite, mild increases in irritability.
Serious Side Effects for norepinephrine reuptake inhibitors (Rare)
Large increases in irritability, suicidal ideation, liver problems.